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Panama City, Panama

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Luxury hotels in Panama City

11 hand-picked hotels with breakfast, upgrades and hotel credit when you book with us.

Panama City guide

The Panama Canal and Casco Viejo

Watch ships climb the Miraflores Locks, then explore the colonial old town by night.

The Panama Canal is the most cited sight in Panama City, and the Miraflores Locks visitor centre, just outside the city, is the place to watch huge ships rise and fall between the oceans. Mornings and mid-afternoons usually bring the most transits.

Casco Viejo, the colonial old town and a UNESCO site, has restored plazas, churches and rooftop bars looking at the modern skyline. Add the Biomuseo designed by Frank Gehry and a boat trip on Gatún Lake, and travel in the dry season, from December to April.

The Panama Canal by boat

A partial transit of the Panama Canal by boat, rising and falling through the Miraflores and Pedro Miguel locks alongside giant ships, is one of the most cited experiences in Panama, offered on certain days of the week. Full transits run occasionally.

Gatún Lake, the artificial lake at the heart of the canal, can be explored by small boat to see monkeys, sloths and birds on its islands. The Soberanía National Park and the Pipeline Road are famous for birdwatching, a short drive from the city.

San Blas and the Guna Yala islands

The San Blas archipelago, more than 300 islands off Panama's Caribbean coast governed by the Guna people, is the most cited excursion from Panama City: white sand, turquoise water and palm trees, reached by a short flight or a drive through the jungle and a boat.

Accommodation is simple and run by Guna communities, who keep their customs; their molas, hand-sewn textile panels, are prized. Respecting local rules and photography etiquette is essential, and day trips or overnight stays can be arranged.

Where to stay

11 luxury hotels in Panama City with VIP benefits

Book through The Prime Traveler and pay what the hotel charges on its own website, with extras you do not get by booking direct.

Hotel creditA property credit to spend on dining or the spa, when the program includes it.
Breakfast for twoDaily breakfast for two guests on participating programs.
UpgradeA room upgrade on arrival, subject to availability.
Flexible timesEarly check-in and late check-out when the hotel can offer it.

Benefits vary by hotel and program. Every proposal shows exactly what applies to your stay, at the same rate the hotel charges on its own website.

Sofitel Legend Casco Viejo
Sofitel

Sofitel Legend Casco Viejo

1 MICHELIN KeyAccor Preferred
Hotel La Compañia
Hyatt

Hotel La Compañia

Hyatt Privé
Hyatt Regency Panama City
Hyatt Regency

Hyatt Regency Panama City

Hyatt Privé
JW Marriott Panama
JW Marriott

JW Marriott Panama

Marriott Luminous
Marriott Panama Hotel
Marriott

Marriott Panama Hotel

Marriott Luminous
Sofitel

Sofitel Legend Casco Viejo - Panama City

Accor Preferred
Sofitel

Sofitel Legend Casco Viejo Panama

Accor Preferred
The Buenaventura Golf and Beach Resort Panama, Autograph Collection
Autograph Collection

The Buenaventura Golf and Beach Resort Panama, Autograph Collection

Marriott Luminous
The Santa Maria, a Luxury Collection Hotel and Golf Resort, Panama City
The Luxury Collection

The Santa Maria, a Luxury Collection Hotel and Golf Resort, Panama City

Marriott STARS
W Panama
W Hotels

W Panama

Marriott Luminous
Waldorf Astoria Panama
Waldorf Astoria

Waldorf Astoria Panama

Hilton for Luxury

MICHELIN Key status checked on the MICHELIN Guide website in October 2026.

Gastrotrip

Where to eat in Panama City

Some of the city's most celebrated tables. With a Gastrotrip we build a day-by-day restaurant route around your hotel, checked by hand.

  • Cantina del Tigre
    #47 Latin America's 50 Best Restaurants 2025
  • Maito
    #18 Latin America's 50 Best Restaurants 2025

Plan a Gastrotrip →

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